Preparing for the Future: Trends that are Re-Shaping the Industry

The Future of Pharma

PwC report: From Vision to Decision: Pharma 2020

PwC recently published its latest report on the future of the pharmaceutical industry, titled “From Vision to Decision: Pharma 2020”. Since 2007 PwC has been studying the challenges and major trends the pharmaceutical industry faces. The report provides an in-depth look at the future for the industry, and below I’ve highlighted five major trends from the PwC report that are reshaping the marketplace.

1. Instances of chronic disease are increasing, placing even greater pressure on already stretched healthcare budgets.

75% of healthcare expenditures are related to chronic disease, according to the Centers for Disease Control and Prevention. In 2010, healthcare expenditures in the US neared $2.6 trillion, and accounted for 17.9% of the US gross domestic product (according to the Centers for Medicare and Medicaid Services). New ideas and tools are needed to help us decrease healthcare costs, while increasing the effectiveness of our healthcare system.

Life sciences companies can contribute solutions in the form of disease management and patient adherence programs. Industry experts agree that one way to decrease future healthcare costs is to boost patient engagement in managing their conditions and increase patient adherence rates.

2. Healthcare policy-makers and payers are increasingly mandating what doctors can prescribe.

One part of the puzzle for decreasing our healthcare costs is to standardize treatment approaches. There are many ways that treatment approaches can be standardized, and they most likely will include following recommended treatment guidelines, product-specific outcomes data, and pricing negotiations with manufacturers.

Life science companies need to be prepared for this shift. Know how your product compares to its competitors. Offer programs that enhance patient outcomes. This demonstrates partnership and that the company stands behind the products they offer.

3. A growing number of healthcare payers are measuring the pharmacoeconomic performance of different medicines.

Widespread use of electronic medical records will give them the data they need to insist on outcomes-based pricing. This is a game-changer for manufacturers, as they will have less power to set prices for their products. New digital tools will provide new options for managing disease and wellness; as well as provide the ability to capture outcomes data at the practice, institution, and health system level.

4. Boundaries between different forms of healthcare are blurring as clinical advances render previously fatal diseases chronic and the self-medication sector expands.

The entire healthcare industry is being transformed. Various factors are converging to change how healthcare is delivered. The center of this transformation is the patient, which when engaged and empowered to manage their health is a critical success factor. Digital health tools and new scientific understanding, which translates into novel and innovative treatments, enable these transformations.

Think about patients at the heart of your program. Understand patient challenges in managing their health and condition. Additionally, expand your view to encompass the entire healthcare system. Understanding shifts in healthcare delivery models, new digital tools and applications, and how patients are using these to manage their condition will help you to develop programs that provide value.

5. Governments are beginning to focus on prevention rather than treatment.

No longer is the focus on treating a condition. Significant advances have been made in screening and diagnostic testing for various cancers. Additionally, there is evidence to support that many chronic conditions are exacerbated, and in some cases caused by, poor lifestyle choices and decisions. Payers are looking to prevention and wellness initiatives as mechanisms for decreasing future healthcare costs.

Life sciences companies can contribute solutions in the form of disease management and wellness programs. These programs boost patient engagement in managing their conditions, and ultimately lead to decreased healthcare spending in the future.

These trends compound the challenges the industry already faces. There are many opportunities if the industry can look beyond their traditional role of providing new medicines. Life science companies that shift their focus to patients and providing innovative healthcare solutions will be successful in the year 2020.

I want to hear your thoughts. Do you agree that the trends highlighted are re-shaping the healthcare industry? What are you and your company doing to prepare for these shifts? Are there trends that you’d include on this list? This is an important discussion, so please share your thoughts.

Wanted: Technologies that Empower Patients

Dr. Cafazzo talks about empowering patients

Inspiring TEDxToronto talk provides examples of technologies that engage patients and help them live well.

I ran across an inspiring presentation by Dr. Joseph Cafazzo on the intersection of patients, healthcare providers, hospitals, and technology to empower patients to live better lives. This presentation was part of the recent TEDxToronto meeting. Dr. Cafazzo is the Lead for the Centre for Global eHealth Innovation, a state-of-the-art research facility devoted to the evaluation and design of healthcare technology in Toronto, Canada.

In the presentation Dr. Cafazzo shares that 75% of healthcare spending is spent treating seven conditions including…

* Diabetes
* Kidney disease
* High blood pressure
* Heart failure
* Lung disease
* Mental health
* Cancer

In most cases these are chronic conditions that need to be managed over a period of time. With appropriate care and adherence to medication, healthcare spending on these conditions can be decreased and patients can live well. For this to take place healthcare providers and hospitals need patients that are engaged and empowered to manage their health.

Dr. Cafazzo is a leading researcher on the use of technology to facilitate patient self-care of complex chronic conditions. In the video he shares several technologies that have made a significant impact to empower patients to manage their condition(s).

We live in exciting times where technology is stimulating monumental progress. Many new technologies are available to help patients be engaged and empowered to manage their health. Effective solutions are needed, and patients need options so they can select the tools that meet their needs and preferences from mobile health sites, app-based health management tools, telehealth devices, educational websites, to nurse educator programs that provide 24/7 assistance to answer patient questions.

At Tunstall AMAC we are focused on helping build and maintain relationships with patients, caregivers, and healthcare providers to drive awareness and knowledge, support patient adherence, and empower patients to take charge of their health. We offer a wide-variety of personal emergency response and telehealth devices that can be used in the home-setting, and we provide 24/7 monitoring and click-to-chat support services to provide support, information, and educational materials to patients, providers, and payers.

I’d like to hear your thoughts on the use of technology to engage patients and empower them to manage their health. Have you, or your company, used these technologies? If so, please share your insights and experiences.

Look to the Future: Physicians Recommend Mobile Apps

Apps for Health Management

Early-adopting physicians recommend mobile apps to enhance patient compliance and outcomes

There is evidence that adults in the US are using cell phones and smartphones to manage their health, and use is growing at a moderate pace. A recent blog post shared results from the Mobile Health 2012 survey, which was published by The Pew Internet and American Life Project. The findings from this survey offer significant insights into how US consumers use their cell phones and smartphones to access health information and health apps. Two key findings that jumped out to me are…

* 31% of cell phone users use their phone to search for health information (in 2010 it was only 17%)

* 19% of smartphone owners have at least one health app on their phone. Exercise, diet, and weight apps are the most popular

As the healthcare industry shifts to outcomes-based payment models, healthcare providers and payers will look for effective and economical ways to help patients better manage their health. Increasing patient adherence to treatment is a primary area that healthcare providers and payers are interested in impacting.

Recently, a post titled “When the Rx is an App” was published on the American Medical News blog (which is published by the American Medical Association). This post focuses on forward-thinking physicians recommending apps to help patients manage their condition, track medication adherence, and monitor their symptoms and vital signs. There are no definitive numbers on how many physicians recommend apps to their patients, but no doubt there is opportunity for apps as a part of a comprehensive patient adherence program. App-based health management tools are convenient and the learning curve for many patients is minimal. Patients carry their smartphones with them and are in the habit of using their smartphones to access e-mail, apps, and search for information.

As the life science industry continues to focus on patient outcomes, with an emphasis on adherence and compliance, there are opportunities for life science companies to provide significant value to patients, healthcare providers, and payers. App-based health management tools are just one component of a potential solution. Effective solutions will include various components so patients can select the tools they are most comfortable with including mobile health sites, telehealth devices, educational websites, and nurse educator programs that provide 24/7 assistance to answer patient questions.

Currently, there are apps that collect patient information such as heart rate, weight, calories burned, calories consumed, etc. that can be shared with healthcare providers during office visits. In the future, technologies such as telehealth devices and apps will summarize collected patient information, send it to healthcare providers, and upload the information directly into electronic health records. With these advances healthcare providers receive accurate patient-specific information that can be used to guide treatment discussions and decisions.

At Tunstall AMAC we are focused on helping build and maintain relationships with patients, caregivers, and healthcare providers to drive awareness and knowledge, support patient adherence, and empower patients to take charge of their health. We offer a wide-variety of personal emergency response and telehealth devices that can be used in the home-setting, and we provide 24/7 monitoring and click-to-chat support services to provide support, information, and educational materials to patients, providers, and payers.

I’d like to hear your thoughts on the use of apps to manage an individual’s health. Do you use healthcare-related apps? Is your company providing these services now? Is your company likely to provide them in the future? Please share your questions and comments, and let’s all learn from each other.

Smartphones: Fertile Ground for Health Information

Interesting stats on smartphone usage - more below

Pew Internet and American Life Project finds half of smartphone owners use their devices to get health information.

The Pew Internet and American Life Project recently published results from the Mobile Health 2012 survey. The findings from this survey offer significant insights into how US consumers use their smartphones to access health information and health apps. These findings are evidence that life science companies have significant opportunities to provide value-added services and products that help patients improve their health.

Key findings from the Mobile Health 2012 survey include…

* 85% of US adults own a cell phone
  - 53% are smartphones

* 31% of cell phone users use their phone to search for health information
  - In 2010 only 17% of cell phone users used their phones to search for health information
  - 52% of smartphone owners access health information via their smartphone

* 19% of smartphone owners have at least one health app on their phone
  - Exercise, diet, and weight apps are the most popular

* 9% of cell phone owners receive text updates and alerts about their health or medical issues
  - 80% of cell phone owners send and receive text messages

*  Those most likely to have signed up for health text alerts...
  - Women between the ages of 30 and 64
  - Smartphone owners

* Those most likely to use cell phones to search for health information…
  - Caregivers
  - Those who recently faced a medical crisis
  - Those who recently experienced a significant change in their physical health

Clearly adults in the US are more often using their cell phones and smartphones to manage their health, and use is growing at a moderate pace. As the life science industry continues to focus on patient outcomes, with an emphasis on adherence and compliance, there are opportunities for life science companies to provide mobile healthcare apps and services that provide significant value to patients, healthcare providers, and payers.

Key areas to consider when planning mobile health initiatives …

Mobile health sites and apps can have a significant impact; however, these are just two components of a potential solution. There are new technologies, such as telehealth devices that are powerful tools or capturing and sharing information between patients and healthcare providers. Additionally, don’t overlook the importance of educational websites and nurse educator programs that provide 24/7 assistance to answer patient questions.

At Tunstall AMAC we are focused on helping build and maintain relationships with patients, caregivers, and healthcare providers to drive awareness and knowledge, support patient adherence, and empower patients to take charge of their health. We offer a wide-variety of personal emergency response and telehealth devices that can be used in the home-setting, and we provide 24/7 monitoring and click-to-chat support services to provide support, information, and educational materials to patients, providers, and payers.

I’d like to hear your thoughts on mobile health information. Is this something you’re doing or considering as a value-added service? Please share your questions and comments, and let’s all learn from each other.

Look to the Future: Sharing Physician Visit Notes with Patients Improves Engagement and Adherence

More transparency and sharing of information is the way of the future in healthcare. A simple option is to allow patient’s access to their visit notes that physicians keep as a part of their medical record. Patients have a right to see their entire medical record including physician’s notes; however, this doesn’t regularly happen.

Very little is known about the impact on physicians and patients when they are allowed to read physician’s notes from their visits. There are a number of questions including…

1)  Would patients be confused or offended by the information included in physician’s notes?

2)  Would physicians feel they need to spend more time in writing their notes and would they experience increases in the number of questions they receive from patients?

To answer these questions a year-long study was launched to provide patients with electronic access to the physician’s notes from their visits. The study results were recently published on-line in the Annals of Internal Medicine.

Below are the key takeaways from this important study…

* 105 physicians and 13,564 patients participated from three sites in the US

* 11,797 patients (87%) opened at least one physician visit note

*  Of the 11,797 patients that opened at least one note, 5,391 (47%) completed a post-intervention survey

* Of the patients completing post-intervention surveys…
   - 77% to 87% of patients across the three sites reported that open notes helped them feel more in control of their care
   - 60% to 78% of those taking medications reported increased medication adherence
   - 1% to 8% reported that the notes caused confusion, worry, or offense
   - 20% to 42% of patients reported sharing notes with others

* The physicians reported...
   - The volume of electronic messages from patients did not change
   - 0% to 5% from the three study sites had longer patient visits
   - 0% to 8% from the three sites increased time spent addressing patients’ questions outside of visits
   - 3% to 36% changed documentation content
   - 0% to 21% took more time to write visit notes

This study is important because it demonstrates that increased information sharing between physicians and patients increases patient engagement. The impact of this study is…

* A significant number of patients (ie, 60% to 78%) reported increased adherence to medications. Historically, only 43% of patients that start a prescription therapy are continuing that therapy 6 months later.

* The majority of patients (77% to 87%) felt that open notes helped them to feel more in control of their care. This is incredibly meaningful and a key component to empowering patients to take control of their health.

* Overall physicians saw no more than a modest effect on their work lives by sharing their visit notes with patients. This data should help physicians overcome concerns they have in adopting this practice.

 Changes in the healthcare industry are driving the emphasis on decreasing healthcare costs and enhancing patient outcomes. Patient engagement and adherence are critical to achieving these goals, and this study supports open sharing of physician visit notes can have an impact with little additional time investment from physicians.

In the future, the industry must support initiatives that empower patients to take responsibility for managing their health. This is a very personal issue, and what motivates one individual may not work to motivate another. Innovative ideas are needed. Ultimately, many approaches will be combined to form a customized solution that is effective for an individual patient.

At Tunstall AMAC we are focused on helping build and maintain relationships with patients, caregivers, and healthcare providers to drive awareness and knowledge, support patient adherence, and empower patients to take charge of their health. We offer a wide-variety of personal emergency response and telehealth devices that can be used in the home-setting, and we provide 24/7 monitoring and click-to-chat support services to provide support, information, and educational materials to patients, providers, and payers. Our services combined with open sharing of physician’s notes can increase patient empowerment.

We recently published a white paper on how to develop successful patient and caregiver support programs, as well as emerging trends being used to deliver customized and personalized experiences for patients. If you’d like a copy of the white paper titled “Increase Patient Adherence and Do More with Less”, please click to request it.

I’d like to hear your thoughts on the open notes study. Do you think this practice is likely to be widely adopted by physicians? What other innovative solutions do you see for empowering patients to take responsibility for managing their health?

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Full-Speed Ahead: The Shift to Patient-Centric and Personalized Marketing Programs

Read a new article in PharmaVOICE magazine about segmentation advances and the value of personalizing marketing programs

Changes in the industry are shifting the goals of marketing programs to focus on the patient, and to provide meaningful outcomes. To do this, the focus must be on getting the right patient on the right treatment. Advances in technology are fueling exciting changes in how effectively marketers segment and message to their audiences. Real-time data capture empowers decision-making and increases the effectiveness of marketing programs.

The industry has used the decile model for segmentation for years, and in a world of hard-to-reach and no-see physicians this approach is no longer effective. Technological advances provide…  

     * Insights into the number of “appropriate” patients a provider has in their practice 
     * A better understanding of patient behavior so that marketers can deliver more
        compelling messages and valuable programs

As the industry continues to evolve marketing programs to be more patient-centric, delivering personalized information and messages takes on an even greater importance. The key to effective marketing programs is delivering value, and the starting point is to understand patient behavior. This understanding allows marketers to provide programs that meet their needs and helps them overcome their challenges. Valuable and relevant programs foster patient commitment and trust.

There is an article in the October 2012 issue of PharmaVOICE magazine (it’s available on-line) that shares expert insights on advances in segmenting and personalizing marketing efforts. The article provides an excellent overview of the technological changes that empower better segmentation, as well as insights into the impact personalization can have in enhancing the effectiveness of programs.

There are many options for personalized marketing programs. As a pharmaceutical call center, we provide opportunities for patients and caregivers to interact personally with our nurse educators and care counselors at their convenience.

I’d like to hear how you are personalizing your marketing activities. Also, are you using advances in technology to fine-tune your market segmentation activities? If so, what insights have you found along the way that helped you to better understand the patient journey? Did you incorporate these findings into your programs?

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Evolving Pharma Sales Models: The Customer is King

How pharmaceutical, biotechnology, and medical device products are sold is changing and it will continue to do so for the foreseeable future. There are many factors driving this change, and two of the most significant are healthcare reform changes and that healthcare providers are demanding meaningful interactions with company representatives. Life science companies are developing new sales models that aren’t solely a “sales pitch”. Rather, the interaction is “customer-centric” and based on meeting the customer’s needs and providing value.

Evolving your sales model to be focused on meeting customer needs is much more than just adapting your sales messages to address the latest concerns heard in the field. This is a fundamental mindset change, and life sciences companies have think about what it is they are offering and delivering. In the future our healthcare system will be focused on patient outcomes and cost. This environment requires the life science industry to provide programs that support treatments to improve patient outcomes, provide value, and decrease costs.

Patient adherence is an important driver in improving patient outcomes and decreasing future healthcare costs, but it is not the only one. In many disease-states and conditions there are health, wellness, and lifestyle factors that contribute to long-term improvement in outcomes and decreases in healthcare expenditures. There is an opportunity, and need, for life sciences companies to partner with patients, providers, and payers to address health, wellness, and lifestyle factors.

There are many programs that can be developed and implemented that will improve patient outcomes. To create meaningful programs patients can “stick to”, think about these areas…

* Understand the barriers patients face in remaining adherent and compliant with therapy.

* Plan programs that support patients on their treatment journey, and help them adhere to treatment.

* Develop patient support programs that are a resource and guide for patients during their treatment journey.

I encourage you to think holistically about the challenges of patients, providers, and payers and design programs to meet these broad needs. As life science companies look to evolve their sales models to meet customers’ needs and provide meaningful interactions, the need for programs that support patients, providers, and payers will increase. Provide solutions, through your product and its related services, to manage or overcome the broad healthcare challenges your customers face.

There are many options for providing programs that enhance patient outcomes. As a pharmaceutical call center, we provide as needed call-in support for patients, caregivers, and healthcare providers to answer questions about a product and its side effects, enroll patients in a support program, connect patients with healthcare providers in their local area, and connect patients with co-pay assistance resources. Our experiences show that within 6 months of implementing a patient support program patient adherence increases 10% to 15%. Patient adherence to treatment decreases future healthcare costs related to treating complications from earlier non-adherence.

There was an interesting article recently published on Pharmaceutical Executive on-line that looks at the evolving nature of pharmaceutical sales forces as they evolve to a more “customer-centric” approach. If you are interested in learning more about one model for moving in this direction you can access the article here.

I’d like to hear from you. Are you adding programs to support patients as a part of your marketing and sales efforts? If you are, what kinds of initiatives and programs are you planning? Please join the conversation and share your thoughts and challenges. We can all learn from each other. Alternatively, if you have specific needs you’d like to discuss with me you can reach me directly at louis.shapiro@tunstallamac.com.

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Hit the Target to Drive Action and Engagement

Lately, I've been thinking about how to drive customer action and engagement. Given recent advances in technology there are many tools available to connect the life sciences industry with their customers on an individual level. For me, the challenge is in how to maximize the impact of these tools to meet the needs of patients, caregivers, and healthcare providers.

I have seen more about behavioral marketing lately, which at its core is focused on figuring out what customers want and providing customers with that in the manner that they want it. Behavioral marketing is beautifully simple and effective, if done correctly. However, the challenging part of behavioral marketing is in answering the questions of what it is that customers want and how to deliver that.

We use behavioral marketing concepts to design programs that meet our clients’ needs and goals. These concepts can easily be implemented to design impactful programs, and below I offer a few specific and practical suggestions on how to do this.

1. Clearly articulate the program’s goals—Clear program goals empower program design and ensure that the program’s results can be measured. If the primary goals of your program are to drive customer engagement and action then behavioral marketing will help you achieve those goals.  

2. Understand the patient journey—Seek to understand how the daily lives of patients are impacted by the disease or condition, identify activities they perform each day, and understand the interactions between patients, healthcare providers, and caregivers. These insights provide valuable glimpses into challenges and unmet needs for patients, healthcare providers, and caregivers.  

3. Offer solutions to overcome patient challenges—Programs designed to help patients overcome challenges are meaningful and valuable. As you design programs think about how the program will be valuable over time. Consider and plan to evolve the program over time to remain relevant and engaging for patients.  

4. Understand how patients like to receive information and support—Seek information on how patients prefer to research information. Do they prefer to do this themselves on-line or through social media channels? Alternatively, do patients prefer to talk with someone about their educational or support needs? Knowing patients’ preferences empowers you to develop appropriate tools and resources that patients utilize, engage, and come to trust. I encourage you to think about integrating options such as robust amounts of information on-line and offering click-to-chat or toll-free telephone access to live representatives. With health and wellness concerns, it’s important not to overlook the power of personal interactions.  

5. Leverage data for insights and decisions—Do not stop gathering and analyzing data. Carefully review data for insights into the needs and preferences of patients, caregivers, and healthcare providers. Rely on data for key insights in designing your program. Once the program is designed and operating continue to seek data for insights into how the program is performing and if updates are needed.

There is an interesting article in the September 2012 issue of PharmaVOICE magazine on behavioral marketing. The article provides insights into developing successful behavioral marketing campaigns, and you can access it here.

Do you have a challenge that might benefit from a program designed with behavioral marketing concepts? If so, please post a comment and share your challenge. Alternatively, please reach out to me to discuss your situation. You can reach me directly at louis.shapiro@tunstallamac.com.

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Budget Planning: Creating Impact with Less Investment

Declining Patient Adherence is a Key Concern

It’s August and many of us are in the midst of budget planning season. We are all aware of the reality facing the life sciences industry—more drugs coming off patent leading to less revenue and increasing costs to develop new treatments. Now more than ever, life science companies are faced with the need to do more with less. For marketers this means maximizing the impact of each program.

My advice to clients is to initially focus on programs that are quick to impact such as patient retention, attracting appropriate patients to consider your product, and maximizing the efficiency of your sales force. Below are a few specific programs you should consider.

Begin with patient compliance and adherence to therapy. It has been reported that compliance to therapy averages between 50% and 65%. There is a tremendous opportunity to increase the number of patients that adhere to treatment. The added benefit is it is much less expensive to keep patients on treatment than it is to attract new patients. To increase patient compliance and adherence consider…

* Patient support programs—these programs focus on patients and help them meet their needs and overcome their challenges. As a pharmaceutical call center we have healthcare-trained representatives available 24/7 and 365 days/year to answer patient questions and provide materials about their condition, treatment, side effects, and even can direct them to reimbursement assistance programs if they need it.

Support DTC marketing efforts and make it easy for patients to act on the awareness built by the advertising campaigns. To increase the effectiveness of your DTC marketing programs consider…

* Adding pharmaceutical call center support to handle inquiries from your advertising campaigns. A pharmaceutical call center we can answer patient questions, and can also provide referrals to physicians and specialists located near the patient’s home or work.

* Including click-to-chat support through websites. Make it easy for patients to ask questions and receive quick replies when they are interacting with one of your websites. Click-to-chat functionality provides real-time interactions, which is a tremendous advantage. As a pharmaceutical call center we can provide healthcare-trained representatives to answer patient questions submitted through websites and can provide links to materials and referrals to physicians and specialists too.

Maximize your field-based sales force so they focus on providing value to healthcare providers. To increase the effectiveness of your field-force consider…

* Partnering with a pharmaceutical call center to drive action with healthcare providers such as booking appointments for sales representatives and enrolling sites in a study or patient support program.

* Shifting administrative tasks such as replenishing samples and overseeing distribution and fulfillment. Our call center representatives reach out to healthcare providers on a regular basis to ensure they have adequate supplies of samples and materials. Additionally, we can oversee database updates and targeting and cleansing activities too.

The challenge to do more with less will continue for the foreseeable future. The formula for success is to create the most value from our investments. There are many opportunities to create value, and I have shared a few of my thoughts on how a pharmaceutical call center partner can help. I’d like to hear from you. What are your challenges? How are you creating more value for your investment?

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Fact: Healthcare Is Changing

Efforts to reform healthcare are moving forward as it is clear that as a nation we must decrease healthcare costs. Right now there are more questions than answers about the impact of the Affordable Care Act (ACA) that the US Supreme Court recently upheld. One thing is clear—the US healthcare system is changing. Below are my thoughts on three key areas the life science industry must prepare for.

Articulate the value of your product.

Conventional end points of safety, efficacy, and quality of life are no longer sufficient. Be prepared to demonstrate cost-effectiveness or cost-avoidance.

Implementation tips...

1) Work collaboratively with your colleagues in marketing, managed care marketing, pharmacoeconomics, clinical affairs, medical affairs, and regulatory to understand the data that is desired by various stakeholders when they are determining if a product is valuable or not. Develop plans to obtain the needed data.

2) Determine which patients are most likely to benefit from your product. Communicate to healthcare providers the patients that are most likely to benefit from treatment. Additionally, assist with screening and referring appropriate patients to local physicians or study sites.

Plan for government rebate plans and pricing controls.

If your treatment is expensive, be prepared for limitations on its use compared to less expensive alternatives.

Implementation tips...

1) Adjust your forecasts

2) Begin working on how to articulate the value of your product (see above for insights)

Provide programs that enhance outcomes for individual patients.

Shift your focus to taking care of patients and improving their outcomes. Patients will stay on treatment and future healthcare expenses resulting from patient non-adherence will decrease.

Implementation tips...

1) Plan and implement programs that support patients on their treatment journey.

2) Understand the barriers patients face in remaining adherent and compliant with therapy.

3) Develop and implement patient support programs that are a resource and guide for patients during their treatment journey. This can include offering access to healthcare-trained representatives for questions or providing educational materials to help patients continue with treatment.

There are many ways you can articulate the value of your product. Additionally there are many options for providing programs that enhance patient outcomes. As a pharmaceutical call center, we provide as needed call-in support for patients, caregivers, and healthcare providers to answer questions about a product and its side effects, enroll patients in a support program, connect patients with healthcare providers in their local area, and connect patients with co-pay assistance resources. Our experiences show that within 6 months of implementing a patient support program patient adherence increases 10% to 15%. Patient adherence to treatment decreases future healthcare costs related to treating complications from earlier non-adherence.

The June 2012 issue of PharmaVOICE magazine has an article on healthcare reform and the potential impacts of it on the life science industry. If you are interested in additional perspectives on the impact of healthcare reform you can access the article here.

I’d like to hear from you. How are you preparing for the impact of the ACA? What areas have you identified as opportunities? What kinds of initiatives and programs are you planning? Please join the conversation and share your thoughts, challenges, and questions on the ACA implementation. We can all learn from each other.

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ASCO Highlights: Two Innovative Trial Designs

 
The annual scientific meeting for the American Society of Clinical Oncology (ASCO) recently concluded. As expected there was a constant flow of new data being released for products in various stages of development for all forms of cancer. The volume of new data is exciting, even though the decks are stacked against these approaches and their odds for commercial success are slim.

As I scanned articles summarizing data presented at the meeting two studies stood out to me because they have superior efficacy data, but also data on endpoints that answer the question of “value”. These two studies demonstrated bold thinking on the behalf of the companies. First, these companies designed products that are tolerable and don’t take away from patients’ quality of life, which is unheard of for the majority of cancer treatments. Additionally, these companies designed clinical trials to demonstrate efficacy and tolerability, which provides meaningful and valuable data to physicians, payers, and patients.

To proactively seek data to differentiate a product is a risky move. However, this is exactly what payers, physicians, and patients are asking for. We are going to see more of this in the future. The studies also demonstrate the importance of meeting patients’ strong desire for efficacious, tolerable, and safe drugs.

These are tremendous first steps, but in thinking and acting boldly, let’s do more to support patients and caregivers during treatment. We all know the time constraints on healthcare providers, an additional opportunity for life science companies is to provide robust patient and caregiver support programs that educate, inform, and guide patients. Treating cancer is a difficult journey. The more support patients receive the more likely they are to remain on treatment, which dramatically improves their outcomes.

Are you interested in knowing the two studies presented at ASCO that jumped out to me? They are…

1. The study GSK launched in patients with renal cell carcinoma evaluating patient preference for Votrient® (pazopanib) and Sutent® (sunitinib). In the study pazopanib (a late entrant into the market) went head-to-head against sunitinib (the 1st line treatment of choice). Both products have similar efficacy rates. The head-to-head study showed that 70% of patients who completed both treatments prefer pazopanib, 22% of patients that completed both treatments prefer sunitinib, and 8% of patients did not have a preference. The primary reasons patients preferred pazopanib were 1) better quality of life, and 2) less fatigue. This study demonstrates the value of evaluating not only efficacy data, but also patient tolerability preferences too.

2. The Roche/Genentech study with TDM-1, which is the Herceptin® antibody trastuzumab combined with the cytotoxic emtansine. The study of this investigational compound versus Xeloda® (capecitabine) + Tykerb® (lapatinib) in patients with HER2+ relapsed metastatic breast cancer showed a progression-free survival benefit with TDM-1, and lower rates of Grade 3 adverse events (41% versus 57%) and very little gastrointestinal toxicity. This study demonstrates the possibility of developing an efficacious product that has decreased side effects.

I’d like to hear from you. Have you considered, or are planning, a head-to-head trial in order to demonstrate your product's unique differences? Also, what ASCO presentations stood out to you? Please share the studies and why you think these are important trials.

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ASCO: Celebrate Successes and Prepare to Support Patients in the Future

The annual scientific meeting for the American Society of Clinical Oncology (ASCO) starts this weekend in Chicago. This meeting is the premier scientific meeting for new clinical data in oncology. Reflecting on this important meeting I’m reminded of the significant advances that have been made in the last 15 years in treating cancer. Several trends fill me with hope for the future, including…

1) Increasing use of oral therapies
2) Molecularly targeted therapies offer decreased side effects versus traditional chemotherapy
3) The possibility that cancer, in many cases, can be treated as a chronic condition with an emphasis on on-going therapy

Cancer treatment is certainly much more effective, manageable, and tolerable than it was 15 years ago. While there are many advances in oncology treatment to celebrate, significant challenges remain including…  

* Patient adherence to treatment—As more oral treatments are used for treating cancer, patients and their caregivers take on a greater role for ensuring treatments are taken regularly and at prescribed doses. With treatments administered in a physician’s office or medical center the nurses see patients regularly and ensure treatments are administered as prescribed and at appropriate times. 

* Changing needs of patients and caregivers—As patients and caregivers take on more responsibility for administering treatments, they are also taking on more responsibility for monitoring and managing side effects to treatment. This can be a frightening responsibility for caregivers and more can be done to support them in this role.  

* Increased costs for treatment—On average targeted therapies cost significantly more than traditional chemotherapeutic agents. The increased cost is an issue for all stakeholders involved in oncology treatment including patients, caregivers, healthcare providers, payers, and life science companies. Patient co-pay and financial assistance programs are critical in helping many patients pay for their treatment.

For life science companies these challenges are significant, and they are also opportunities to engage with patients, caregivers, and healthcare providers. To begin, ensure you…  

* Understand the patient’s treatment journey, and in particular, the barriers they face in remaining adherent and compliant with treatment 

* Develop and implement comprehensive patient support programs that are a resource and guide for patient’s during their treatment journey  

* Inform and educate healthcare providers on the details of patient and caregiver support programs

As a pharmaceutical call center, we provide as-needed call-in support for patients, caregivers, and healthcare providers to answer questions about a product and its side effects, enroll patients in a support program, and connect patients with co-pay assistance resources. Our Medical Advisory Board works with us to design programs focused on meeting the needs of patients, caregivers, and healthcare providers.

I’d like to hear from you. What challenges does your oncology product(s) face? Please join the conversation and share your thoughts, challenges and questions.

I’ll be in Chicago at the ASCO meeting. If you’ll be at ASCO, please send me an e-mail and we’ll schedule a time to get together. I always enjoy learning about the challenges you're facing.

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